<i>Cupriavidus necator</i>-Produced Polyhydroxybutyrate/Eudragit FS Hybrid Nanoparticles Mitigates Ulcerative Colitis via Colon-Targeted Delivery of Cyclosporine A

• Main Authors: Juho Lee (Author), Aruzhan Saparbayeva (Author), Shwe Phyu Hlaing (Author), Dongmin Kwak (Author), Hyunwoo Kim (Author), Jihyun Kim (Author), Eun Hee Lee (Author), Jin-Wook Yoo (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Polyhydroxybutyrate (PHB) has emerged as a novel material for replacing various plastics used in the medical field. However, its application as a drug-delivery carrier for colitis-targeted delivery has not been explored. In this study, we used biosynthesized PHB combined with Eudragit FS (EFS) and c...