An mRNA Vaccine Encoding Rabies Virus Glycoprotein Induces Protection against Lethal Infection in Mice and Correlates of Protection in Adult and Newborn Pigs.

• Main Authors: Margit Schnee (Author), Annette B Vogel (Author), Daniel Voss (Author), Benjamin Petsch (Author), Patrick Baumhof (Author), Thomas Kramps (Author), Lothar Stitz (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rabies is a zoonotic infectious disease of the central nervous system (CNS). In unvaccinated or untreated subjects, rabies virus infection causes severe neurological symptoms and is invariably fatal. Despite the long-standing existence of effective vaccines, vaccine availability remains insufficient...