Importance of Binding Affinity for the Activity of a Metallodendritic Chemical Nuclease

• Main Authors: Yi-Hsuan Tang (Author), Sodio C. N. Hsu (Author), Po-Yu Chen (Author), Si-ting Liou (Author), Hui-Ting Chen (Author), Carol Hsin-Yi Wu (Author), Chai-Lin Kao (Author)
• Format: Book
• Published: MDPI AG, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A family of <i>bis</i>(2-pyridyl)amino-modified poly(amidoamine) dendrimer Cu complexes was prepared, and their chemical nuclease activities and binding affinity (<i>K_b</i>) levels for DNA plasmid were investigated. The <i>K</i><sub>b&...