Slow Elevation in Protein C Activity without a PROC Mutation in a Neonate with Intracranial Hemorrhage

• Main Authors: Erika Uehara (Author), Hiro Nakao (Author), Yusuke Tsumura (Author), Hisaya Nakadate (Author), Shoichiro Amari (Author), Hideshi Fujinaga (Author), Yoshiyuki Tsutsumi (Author), Dongchon Kang (Author), Shouichi Ohga (Author), Akira Ishiguro (Author)
• Format: Book
• Published: Thieme Medical Publishers, Inc., 2018-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Severe protein C (PC) deficiency leads to purpura fulminans and stroke in newborns. However, the clinical impact of plasma PC activity on the development of neonatal cerebral disease remains elusive. We report a case of hemorrhagic stroke associated with neonatal asphyxia and severe PC deficiency. P...