Icariside II, a Naturally Occurring SIRT3 Agonist, Protects against Myocardial Infarction through the AMPK/PGC-1α/Apoptosis Signaling Pathway

• Main Authors: Yeli Li (Author), Linying Feng (Author), Dianyou Xie (Author), Mu Lin (Author), Yiqi Li (Author), Nana Chen (Author), Danli Yang (Author), Jianmei Gao (Author), Yizhun Zhu (Author), Qihai Gong (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Myocardial infarction (MI) refers to the death of cardiomyocytes triggered by a lack of energy due to myocardial ischemia and hypoxia, and silent mating type information regulation 2 homolog 3 (SIRT3) plays an essential role in protecting against myocardial oxidative stress and apoptosis, which are...