Nuciferine Effectively Protects Mice against Acetaminophen-Induced Liver Injury

• Main Authors: Zixiong Zhou (Author), Jing Qi (Author), Yajiao Wu (Author), Chutao Li (Author), Wenqiang Bao (Author), Xiaohuang Lin (Author), An Zhu (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acetaminophen (APAP) overdose still poses a major clinical challenge and is a leading cause of acute liver injury (ALI). N-acetylcysteine (NAC) is the only approved antidote to treat APAP toxicity while NAC therapy can trigger side effects including severe vomiting and even shock. Thus, new insights...