Prevention of Avian Retrovirus Infection in Chickens Using CRISPR-Cas9 Delivered by Marek's Disease Virus

• Main Authors: Kai Li (Author), Yongzhen Liu (Author), Zengkun Xu (Author), Yu Zhang (Author), Yongxiu Yao (Author), Venugopal Nair (Author), Changjun Liu (Author), Yanping Zhang (Author), Yulong Gao (Author), Xiaole Qi (Author), Hongyu Cui (Author), Li Gao (Author), Xiaomei Wang (Author)
• Format: Book
• Published: Elsevier, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reticuloendotheliosis virus (REV) is an avian retrovirus that causes an oncogenic, immunosuppressive, and runting-stunting syndrome in avian hosts. The co-infection of REV and Marek's disease virus (MDV), an oncogenic herpesvirus in chickens, further increases disease severity and reduces MDV v...