Poly(ADP-Ribose)Polymerase (PARP) Inhibitors and Radiation Therapy
Poly(ADP-ribose)polymerase-1 (PARP1) is a DNA repair enzyme highly expressed in the nuclei of mammalian cells, with a structure and function that have attracted interest since its discovery. PARP inhibitors, moreover, can be used to induce synthetic lethality in cells where the homologous recombinat...
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| Main Authors: | , , , |
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| Format: | Book |
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Frontiers Media S.A.,
2020-03-01T00:00:00Z.
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