Evaluation of a Conformationally Constrained Indole Carboxamide as a Potential Efflux Pump Inhibitor in <i>Pseudomonas</i> <i>aeruginosa</i>

• Hlavní autoři: Yongzheng Zhang (Autor), Jesus D. Rosado-Lugo (Autor), Pratik Datta (Autor), Yangsheng Sun (Autor), Yanlu Cao (Autor), Anamika Banerjee (Autor), Yi Yuan (Autor), Ajit K. Parhi (Autor)
• Médium: Kniha
• Vydáno: MDPI AG, 2022-05-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Efflux pumps in Gram-negative bacteria such as <i>Pseudomonas aeruginosa</i> provide intrinsic antimicrobial resistance by facilitating the extrusion of a wide range of antimicrobials. Approaches for combating efflux-mediated multidrug resistance involve, in part, developing indirect ant...