Sinomenine Confers Protection Against Myocardial Ischemia Reperfusion Injury by Preventing Oxidative Stress, Cellular Apoptosis, and Inflammation

• Main Authors: Boyu Xia (Author), Qi Li (Author), Jingjing Wu (Author), Xiaomei Yuan (Author), Fei Wang (Author), Xu Lu (Author), Chao Huang (Author), Koulong Zheng (Author), Rongrong Yang (Author), Le Yin (Author), Kun Liu (Author), Qingsheng You (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sinomenine (SIN), an alkaloid extracted from the root of S. acutum. sinomenine, has been shown to have antiarrhythmic, antioxidant, and anti-inflammatory effects in myocardial ischemia-reperfusion injury (MIRI) ex vivo. In this study, we investigated the cardioprotective effects of SIN in an in vivo...