LC-MS/MS method for the quantitation of decitabine and venetoclax in rat plasma after SPE: Application to pharmacokinetic study
This study developed a novel, sensitive and selective LC-MS/MS method for the concurrent determination of DCB and VTX in rat plasma using encorafenib as internal standard (IS). To identify DCB, VTX, and IS, the positive multiple reaction monitoring (MRM) mode was used. Chromatographic separation was...
Saved in:
Main Authors: | Abdulaziz I. Alnasser (Author), Mohamed M. Hefnawy (Author), Abdullah M. Al-Hossaini (Author), Yousef A. Bin Jardan (Author), Adel S. El-Azab (Author), Alaa M. Abdel-Aziz (Author), Abdulrahman M. Al-Obaid (Author), Ibrahim A. Al-Suwaidan (Author), Mohamed W. Attwa (Author), Manal A. El-Gendy (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2023-09-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
High-throughput SPE-LC-MS/MS method for determination of indapamide in human serum
by: Natalija Nakov, et al.
Published: (2013) -
Insights into <i>Clematis cirrhosa</i> L. Ethanol Extract: Cytotoxic Effects, LC-ESI-QTOF-MS/MS Chemical Profiling, Molecular Docking, and Acute Toxicity Study
by: Manal I. Alruwad, et al.
Published: (2024) -
Quantitative Determination of ABT-925 in Human Plasma by On-Line SPE and LC-MS/MS: Validation and Sample Analysis in Phase II Studies
by: Katty Wan, et al.
Published: (2010) -
Evaluation of Alectinib Metabolic Stability in HLMs Using Fast LC-MS/MS Method: In Silico ADME Profile, P450 Metabolic Lability, and Toxic Alerts Screening
by: Mohamed W. Attwa, et al.
Published: (2023) -
LC-MS/MS Estimation of the Anti-Cancer Agent Tandutinib Levels in Human Liver Microsomes: Metabolic Stability Evaluation Assay
by: Attwa MW, et al.
Published: (2020)