Synthesis and antitumor properties of some new N-(5-R-benzyl-1,3-thiazol-2-yl)-4,5-dihydro-1H-imidazole-2-carboxamides

• Main Authors: Volodymyr Ya Horishny (Author), Iryna V Drapak (Author), Taras I Chaban (Author), Yuriy V Ostapiuk (Author), Vasyl S Matiychuk (Author)
• Format: Book
• Published: Universitas Gadjah Mada, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

New N-(5-R-benzyl-1,3-thiazol-2-yl)-2-morpholin-4-yl-2-oxoacetamides have been prepared in good yields via the reaction of N-(5-R-benzyl-1,3-thiazol-2-yl)-2-chloroacetamides with sulfur and morfoline. These compounds react with ethendiamine to form a series of novel N-[5-R-benzyl)-1,3-thiazol-2-yl]-...