3-Arylcoumarin inhibits vascular calcification by inhibiting the generation of AGEs and anti-oxidative stress

• Main Authors: YuFei Li (Author), Yinbo Pan (Author), Liying Wang (Author), Xiaojing Wang (Author), Haiping Chu (Author), Yan Li (Author), Jie Sun (Author), Yanling Mu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective This work aims to screen drugs for preventing and treating vascular calcification. Method: We screened a series of 3-arylcoumarins for the detection of vascular calcification-associated factors using human aortic vascular smooth muscle cells.Results We found that compounds 14 and 32 signif...