Antibody-mediated targeting of the transferrin receptor in cancer cells
Iron is essential for cell growth and is imported into cells in part through the action of transferrin (Tf), a protein that binds its receptor (TfR1 or CD71) on the surface of a cell, and then releases iron into endosomes. TfR1 is a single pass type-II transmembrane protein expressed at basal levels...
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| Main Authors: | , , |
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| Format: | Book |
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Permanyer,
2016-11-01T00:00:00Z.
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