Assessment of E. coli Expression System for Overexpression of Active Recombinant Ocriplasmin

• 主要な著者: Roghayyeh Baghban (著者), Safar Farajnia (著者), Younes Ghasemi (著者), Mojtaba Mortazavi (著者), Naser Samadi (著者), Nosratollah Zarghami (著者)
• フォーマット: 図書
• 出版事項: Tabriz University of Medical Sciences, 2021-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Purpose: Ocriplasmin (Jetrea TM) is a FDA approved recombinant enzyme utilized in the treatment of vitreomacular adhesion (VMA). This is a recombinant C-terminal fragment of human plasmin produced using yeast Pichia pastoris. Since ocriplasmin does not contain any Oor N-glycosylation or some other p...