Serum beta‐defensin‐2 is a biomarker for psoriasis but not subclinical atherosclerosis: Role of IL17a, PI‐3 kinase and Rac1

• Main Authors: Carla J. Pantoja (Author), Haiou Li (Author), Justin Rodante (Author), Andrew Keel (Author), Alexander V. Sorokin (Author), Axel Svedbom (Author), Heather L. Teague (Author), Mona Stahle (Author), Nehal N. Mehta (Author), Martin P. Playford (Author)
• Formato: Livro
• Publicado em: Wiley, 2024-03-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Beta‐defensins (BDs) are antimicrobial peptides secreted upon epithelial injury. Both chemotactic and antimicrobial properties of BDs function as initial steps in host defence and prime the adaptive immune system in the body. Psoriasis, a chronic immune‐mediated inflammatory dise...