Pituitary adenylate cyclase-activating polypeptide type 1 receptor signaling evokes long-lasting nociceptive behaviors through the activation of spinal astrocytes in mice
Intrathecal (i.t.) administration of pituitary adenylate cyclase-activating polypeptide (PACAP) induces long-lasting nociceptive behaviors for more than 60 min in mice, while the involvement of PACAP type1 receptor (PAC1-R) has not been clarified yet. The present study investigated signaling mechani...
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Main Authors: | Tetsuya Ohnou (Author), Masafumi Yokai (Author), Takashi Kurihara (Author), Maiko Hasegawa-Moriyama (Author), Takao Shimizu (Author), Kazuhiko Inoue (Author), Yuki Kambe (Author), Yuichi Kanmura (Author), Atsuro Miyata (Author) |
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Format: | Book |
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Elsevier,
2016-04-01T00:00:00Z.
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