A Phenotypic Analysis of Involucrin-Membrane-Bound Ovalbumin Mice after Adoptive Transfer of Ovalbumin-Specific CD8+ T Cells

• Main Authors: Yujin Nakagawa (Author), Gyohei Egawa (Author), Toshiya Miyake (Author), Saeko Nakajima (Author), Atsushi Otsuka (Author), Takashi Nomura (Author), Akihiko Kitoh (Author), Teruki Dainichi (Author), Jun-ichi Sakabe (Author), Akihiko Shibaki (Author), Yoshiki Tokura (Author), Tetsuya Honda (Author), Kenji Kabashima (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To investigate the mechanism of autoimmunity and peripheral tolerance in the skin, several transgenic mouse strains expressing membrane-bound ovalbumin (mOVA) as an epidermal self-antigen under the control of keratinocyte-specific promotors, such as keratin 5 and keratin 14, were employed in combina...