Gut-Derived Serotonin Contributes to the Progression of Non-Alcoholic Steatohepatitis via the Liver HTR2A/PPARγ2 Pathway

Gut-Derived Serotonin Contributes to the Progression of Non-Alcoholic Steatohepatitis via the Liver HTR2A/PPARγ2 Pathway

The precipitous increase in occurrence of non-alcoholic steatohepatitis (NASH) is a serious threat to public health worldwide. The pathogenesis of NASH has not yet been thoroughly studied. We aimed to elucidate the interplay between serotonin (5-hydroxytryptamine, 5-HT) and NASH. The serum 5-HT leve...

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Main Authors: Lulu Wang (Author), Xiangcheng Fan (Author), Jichun Han (Author), Minxuan Cai (Author), Xiaozhong Wang (Author), Yan Wang (Author), Jing Shang (Author)
Format: Book
Published: Frontiers Media S.A., 2020-05-01T00:00:00Z.
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