Safety, tolerability, and pharmacokinetics of single and multiple topical ophthalmic administration of imatinib mesylate in healthy subjects

Abstract For the long‐term efficacy of dry eye disease treatment, relieving underlying inflammation is necessary. Imatinib mesylate is a novel ophthalmic formulation of imatinib mesylate, which is expected to alleviate inflammation by inhibiting the discoidin domain receptor 1 activity. This study a...

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Main Authors: Joo Young Na (Author), Ki Young Huh (Author), Kyung‐Sang Yu (Author), Joon Young Hyon (Author), Hye Cheong Koo (Author), Jong Ho Lee (Author), Ji Chang You (Author), Jae‐Yong Chung (Author)
Format: Book
Published: Wiley, 2022-05-01T00:00:00Z.
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