The Homeodomain Transcription Factor NKX3.1 Modulates Bladder Outlet Obstruction Induced Fibrosis in Mice

• Main Authors: Mehul S. Patel (Author), Diana K. Bowen (Author), Nicholas M. Tassone (Author), Andrew D. Gould (Author), Kirsten S. Kochan (Author), Paula R. Firmiss (Author), Natalie A. Kukulka (Author), Megan Y. Devine (Author), Belinda Li (Author), Edward M. Gong (Author), Robert W. Dettman (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fibrosis is an irreversible remodeling process characterized by the deposition of collagen in the extracellular matrix of various organs through a variety of pathologies in children, leading to the stiffening of healthy tissues and organ dysfunction. Despite the prevalence of fibrotic disease in chi...