Design, Synthesis, and Biological Evaluation of a Novel VEGFR-2 Inhibitor Based on a 1,2,5-Oxadiazole-2-Oxide Scaffold with MAPK Signaling Pathway Inhibition
Over the past few decades, the development of broad-spectrum anticancer agents with anti-angiogenic activity has witnessed considerable progress. In this study, a new series of pyrazolo[3,4-d]pyrimidines based on a phenylfuroxan scaffold were designed, synthesized, and evaluated, in terms of their a...
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Main Authors: | Mater H. Mahnashi (Author), Fardous F. El-Senduny (Author), Mohammed Abdulrahman Alshahrani (Author), Mahrous A. Abou-Salim (Author) |
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Format: | Book |
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MDPI AG,
2022-02-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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