Deciphering the actions of antiparkinsonian and antipsychotic drugs on cAMP/DARPP-32 signaling

• Main Authors: Gilberto eFisone (Author), Alessandra eBonito-Oliva (Author), Michael eFeyder (Author)
• Format: Book
• Published: Frontiers Media S.A., 2011-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The basal ganglia are affected by several neuropsychiatric and neurodegenerative diseases, many of which are treated with drugs acting on the dopamine system. For instance, the loss of dopaminergic input to the striatum, which is the main pathological feature of Parkinson's disease (PD), is cou...