PARK2 mediates interleukin 6 and monocyte chemoattractant protein 1 production by human macrophages.

• Main Authors: Louis de Léséleuc (Author), Marianna Orlova (Author), Aurelie Cobat (Author), Manon Girard (Author), Nguyen Thu Huong (Author), Nguyen Ngoc Ba (Author), Nguyen Van Thuc (Author), Richard Truman (Author), John S Spencer (Author), Linda Adams (Author), Vu Hong Thai (Author), Alexandre Alcais (Author), Erwin Schurr (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leprosy is a persistent infectious disease caused by Mycobacterium leprae that still affects over 200,000 new patients annually. The host genetic background is an important risk factor for leprosy susceptibility and the PARK2 gene is a replicated leprosy susceptibility candidate gene. The protein pr...