A comparative study of carbonic anhydrase activity in lymphocytes from colorectal cancer tissues and adjacent healthy counterparts

• Main Authors: Giulia Nannini (Author), Viviana De Luca (Author), Chiara D'Ambrosio (Author), Andrea Scaloni (Author), Antonio Taddei (Author), Maria Novella Ringressi (Author), Fabio Cianchi (Author), Fabio Staderini (Author), Clemente Capasso (Author), Amedeo Amedei (Author), Claudiu T. Supuran (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Several carbonic anhydrase (CA, EC 4.2.1.1) isoforms play an essential role in processes connected to tumorigenesis, as they efficiently accelerate the hydration of carbon dioxide to bicarbonate and proton. In this context, examples are CA IX and CA XII, which were proved to be upregulated in many s...