Exploring the role of trifarotene against RAR-α: an investigation of expression pattern and clinicopathological significance of RAR-α in breast cancer

• Main Authors: Nusrat Jan (Author), Shazia Sofi (Author), Adel Abo Mansoor (Author), Adil Abdelrahim (Author), Irshad Ahmad (Author), Abdullah Almilabairy (Author), Fuzail Ahmad (Author), Manzoor Ahmad Mir (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionThe members retinoic acid receptors (RARs) (α, β, and γ) and retinoid X receptors (RXRs) (α, β, and γ) belong to the retinoid receptor family. They regulate the biological action of classical retinoids through nuclear retinoid receptors, a transcription factor that is regulated by ligand...