Preclinical comparison of [177Lu]Lu-rhPSMA-10.1 and [177Lu]Lu-rhPSMA-10.2 for endoradiotherapy of prostate cancer: biodistribution and dosimetry studies

• Autori principali: Alexander Wurzer (Autore), Francesco De Rose (Autore), Sebastian Fischer (Autore), Markus Schwaiger (Autore), Wolfgang Weber (Autore), Stephan Nekolla (Autore), Hans-Jürgen Wester (Autore), Matthias Eiber (Autore), Calogero D'Alessandria (Autore)
• Natura: Libro
• Pubblicazione: SpringerOpen, 2024-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background Radiohybrid PSMA-targeted ligands (rhPSMA) have been introduced as a novel platform for theranostic applications. Among a variety of rhPSMA-ligands developed for radioligand therapy, two stereoisomers [177Lu]Lu-rhPSMA-10.1 and -10.2 have been synthesized and initially characteriz...