Safety, tolerability, pharmacokinetic, and pharmacodynamic characteristics of vutiglabridin: A first‐in‐class, first‐in‐human study

• Main Authors: Joo Young Na (Author), Deok Yong Yoon (Author), Hyounggyoon Yoo (Author), SeungHwan Lee (Author), Kyung‐Sang Yu (Author), In‐Jin Jang (Author), Sang‐Ku Yoo (Author), Youngah Kim (Author), Jaeseong Oh (Author)
• Format: Book
• Published: Wiley, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract This study aimed to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of vutiglabridin, a potential anti‐obesity treatment under development, for the first time in humans. A randomized, placebo‐controlled, single‐ and multiple‐ascending dose study (SAD and MAD, respe...