Development of a nonhuman primate challenge model to evaluate CD8+ T cell responses to an adenovirus-based vaccine expressing SIV proteins upon repeat-dose treatment with checkpoint inhibitors
Targeting immune checkpoint receptors expressed in the T cell synapse induces active and long-lasting antitumor immunity in preclinical tumor models and oncology patients. However, traditional nonhuman primate (NHP) studies in healthy animals have thus far demonstrated little to no pharmacological a...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
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Taylor & Francis Group,
2022-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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