Model-Informed Precision Dosing for Personalized Ustekinumab Treatment in Plaque Psoriasis

• Main Authors: Karine Rodríguez-Fernández (Author), Javier Zarzoso-Foj (Author), Marina Saez-Bello (Author), Almudena Mateu-Puchades (Author), Antonio Martorell-Calatayud (Author), Matilde Merino-Sanjuan (Author), Elena Gras-Colomer (Author), Monica Climente-Martí (Author), Victor Mangas-Sanjuan (Author)
• Format: Book
• Published: MDPI AG, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Objectives: Implementing model-informed precision dosing (MIPD) strategies guided by population pharmacokinetic/pharmacodynamic (PK/PD) models could enhance the management of inflammatory diseases such as psoriasis. However, the extent of individual experimental data gathered during MIPD...