Associations of HLA-A and HLA-B with vancomycin-induced drug reaction with eosinophilia and systemic symptoms in the Han-Chinese population

• Main Authors: Chuang-Wei Wang (Author), Wei-Chen Lin (Author), Wei-Ti Chen (Author), Chun-Bing Chen (Author), Chun-Wei Lu (Author), Hsin-Han Hou (Author), Rosaline Chung-Yee Hui (Author), Jennifer Wu (Author), Chih-Jung Chang (Author), Ya-Ching Chang (Author), Wen-Hung Chung (Author), Taiwan Severe Cutaneous Adverse Reaction Consortium (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Vancomycin is a commonly used antibiotic; however, it can cause life-threatening severe cutaneous adverse reactions, such as drug reaction with eosinophilia and systemic symptoms (DRESS). A previous study has reported a strong association between HLA-A*32:01 and vancomycin-induced DRESS in European...