Benzodioxane-Benzamides as FtsZ Inhibitors: Effects of Linker's Functionalization on Gram-Positive Antimicrobial Activity

• Main Authors: Lorenzo Suigo (Author), William Margolin (Author), Eugenia Ulzurrun (Author), Martina Hrast Rambaher (Author), Carlo Zanotto (Author), Victor Sebastián-Pérez (Author), Nuria E. Campillo (Author), Valentina Straniero (Author), Ermanno Valoti (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

FtsZ is an essential bacterial protein abundantly studied as a novel and promising target for antimicrobials. FtsZ is highly conserved among bacteria and mycobacteria, and it is crucial for the correct outcome of the cell division process, as it is responsible for the division of the parent bacteria...