Liver hydrolysate improves depressive-like behavior in olfactory bulbectomized mice: Involvement of hippocampal neurogenesis through the AMPK/BDNF/CREB pathway

• Main Authors: Osamu Nakagawasai (Author), Kotaro Yamada (Author), Takayo Odaira (Author), Kohei Takahashi (Author), Wataru Nemoto (Author), Wakana Sakuma (Author), Miharu Wakou (Author), Jia-Rong Lin (Author), Koichi Tan-No (Author)
• Format: Book
• Published: Elsevier, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recently, we has reported that AMPK activator has antidepressant effect. Previous our study suggested that liver hydrolysate (LH) activated adenosine monophosphate-activated protein kinase (AMPK) in periphery. However, the effect of LH on depression is unclear. Therefore, we examines whether LH has...