Design, synthesis and evaluation of 2-aryl benzoxazoles as promising hit for the A2A receptor

• 主要な著者: Romain Duroux (著者), Nicolas Renault (著者), Joana Esteves Cuelho (著者), Laurence Agouridas (著者), David Blum (著者), Luisa V. Lopes (著者), Patricia Melnyk (著者), Saïd Yous (著者)
• フォーマット: 図書
• 出版事項: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The development of adenosine A2A receptor antagonists has received much interest in recent years for the treatment of neurodegenerative diseases. Based on docking studies, a new series of 2-arylbenzoxazoles has been identified as potential A2AR antagonists. Structure-affinity relationship was invest...