Design, synthesis and evaluation of 2-aryl benzoxazoles as promising hit for the A2A receptor

• Asıl Yazarlar: Romain Duroux (Yazar), Nicolas Renault (Yazar), Joana Esteves Cuelho (Yazar), Laurence Agouridas (Yazar), David Blum (Yazar), Luisa V. Lopes (Yazar), Patricia Melnyk (Yazar), Saïd Yous (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The development of adenosine A2A receptor antagonists has received much interest in recent years for the treatment of neurodegenerative diseases. Based on docking studies, a new series of 2-arylbenzoxazoles has been identified as potential A2AR antagonists. Structure-affinity relationship was invest...