Effects of Temsavir, Active Moiety of Antiretroviral Agent Fostemsavir, on QT Interval: Results From a Phase I Study and an Exposure-Response Analysis

• Главные авторы: Chakradhar Lagishetty (Автор), Katy Moore (Автор), Peter Ackerman (Автор), Cyril Llamoso (Автор), Mindy Magee (Автор)
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• Опубликовано: Wiley, 2020-07-01T00:00:00Z.
• Предметы: article
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Fostemsavir, a prodrug of human immunodeficiency virus attachment inhibitor temsavir (TMR), is in phase III development in combination with other antiretroviral agents for the treatment of human immunodeficiency virus type I (HIV‐1) infection in heavily treatment‐experienced adults with multidrug‐re...