A Lead-Based Fragment Library Screening of the Glycosyltransferase WaaG from <i>Escherichia coli</i>

• Main Authors: Federico Riu (Author), Alessandro Ruda (Author), Olof Engström (Author), Claudio Muheim (Author), Hani Mobarak (Author), Jonas Ståhle (Author), Paul Kosma (Author), Antonio Carta (Author), Daniel O. Daley (Author), Göran Widmalm (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glucosyl transferase I (WaaG) in <i>E. coli</i> catalyzes the transfer of an α-<span style="font-variant: small-caps;">d</span>-glucosyl group to the inner core of the lipopolysaccharide (LPS) and plays an important role in the biogenesis of the outer membrane. If i...