Single cell RNA-seq reveals cellular and transcriptional heterogeneity in the splenic CD11b+Ly6Chigh monocyte population expanded in sepsis-surviving mice

• المؤلفون الرئيسيون: Haruki Watanabe (مؤلف), Minakshi Rana (مؤلف), Myoungsun Son (مؤلف), Pui Yan Chiu (مؤلف), Yurong Fei-Bloom (مؤلف), Kwangmin Choi (مؤلف), Betty Diamond (مؤلف), Barbara Sherry (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2024-11-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background Sepsis survivors exhibit immune dysregulation that contributes to poor long-term outcomes. Phenotypic and functional alterations within the myeloid compartment are believed to be a contributing factor. Here we dissect the cellular and transcriptional heterogeneity of splenic CD11...