Eplerenone-Mediated Aldosterone Blockade Prevents Renal Fibrosis by Reducing Renal Inflammation, Interstitial Cell Proliferation and Oxidative Stress

Background/Aims: Prolonged elevation of serum aldosterone leads to renal fibrosis. Inflammation also plays a role in the pathogenesis of renal disease. We used a rat model of interstitial renal fibrosis to test the hypothesis that eplerenone-mediated aldosterone blockade prevents renal fibrosis due...

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Main Authors: Hui Chen (Author), Feng Sun (Author), Xiaoshi Zhong (Author), Yuebin Shao (Author), Ashio Yoshimura (Author), Yan Liu (Author)
Format: Book
Published: Karger Publishers, 2013-11-01T00:00:00Z.
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3rd Floor Main Library

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