Metoclopramide-Induced Acute Dystonic Reactions May Be Associated With the CYP2D6 Poor Metabolizer Status and Pregnancy-Related Hormonal Changes

We report two cases of metoclopramide-induced acute dystonia in pregnant women and consider the role of genetic variation in the pathogenesis of the adverse effect. By whole-gene sequencing, we found that both women were CYP2D6 poor metabolizers. We theorize that CYP2D6 governs the risk of metoclopr...

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Main Authors: Eng Wee Chua (Author), Simon P. Harger (Author), Martin A. Kennedy (Author)
Format: Book
Published: Frontiers Media S.A., 2019-08-01T00:00:00Z.
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3rd Floor Main Library

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