Pathway Based Analysis of Mutation Data Is Efficient for Scoring Target Cancer Drugs

• Main Authors: Marianna A. Zolotovskaia (Author), Maxim I. Sorokin (Author), Anna A. Emelianova (Author), Nikolay M. Borisov (Author), Denis V. Kuzmin (Author), Pieter Borger (Author), Andrew V. Garazha (Author), Anton A. Buzdin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite the significant achievements in chemotherapy, cancer remains one of the leading causes of death. Target therapy revolutionized this field, but efficiencies of target drugs show dramatic variation among individual patients. Personalization of target therapies remains, therefore, a challenge i...