Berberine inhibits breast carcinoma proliferation and metastasis under hypoxic microenvironment involving gut microbiota and endogenous metabolites

• Main Authors: Yanfang Sun (Author), QianQian Zhou (Author), Fangming Chen (Author), Xiaoyan Gao (Author), Linjun Yang (Author), Xiaoyan Jin (Author), Michael Wink (Author), Farukh S. Sharopov (Author), Gautam Sethi (Author)
• Format: Book
• Published: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A potential role of berberine, a benzyl isoquinoline alkaloid, in cancer therapy is apparent. Its underlying mechanisms of berberine against breast carcinoma under hypoxia have not been elucidated. We focused on the doubt how berberine restrains breast carcinoma under hypoxia in vitro and in vivo. A...