Impact of Methods of Preparation on Mechanical Properties, Dissolution Behavior, and Tableting Characteristics of Ibuprofen-Loaded Amorphous Solid Dispersions

Impact of Methods of Preparation on Mechanical Properties, Dissolution Behavior, and Tableting Characteristics of Ibuprofen-Loaded Amorphous Solid Dispersions

This study aims to improve the biopharmaceutical, mechanical, and tableting properties of a poorly soluble drug, ibuprofen (IBP), by preparing amorphous solid dispersion (ASD) followed by a sustained-release tablet formulation. A suitable polymer to develop an ASD system was chosen by utilizing the...

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Main Authors: Ajam Uddin (Author), Shimul Halder (Author), Nandita Deb (Author), Harinarayan Das (Author), Madhabi Lata Shuma (Author), Ikramul Hasan (Author), Manik Chandra Shill (Author), Syed Shabbir Haider (Author)
Format: Book
Published: Hindawi Limited, 2024-01-01T00:00:00Z.
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