Sex Differences in the Effects of a Kappa Opioid Receptor Antagonist in the Forced Swim Test

• Главные авторы: Abigail Laman-Maharg (Автор), Alexia V. Williams (Автор), Mikaela D. Zufelt (Автор), Vanessa A. Minie (Автор), Stephanie Ramos-Maciel (Автор), Rebecca Hao (Автор), Evelyn Ordoñes Sanchez (Автор), Tiffany Copeland (Автор), Jill L. Silverman (Автор), Angelina Leigh (Автор), Rodney Snyder (Автор), F. Ivy Carroll (Автор), Timothy R. Fennell (Автор), Brian C. Trainor (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2018-02-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

There is growing evidence that kappa opioid receptor (KOR) antagonists could be a useful class of therapeutics for treating depression and anxiety. However, the overwhelming majority of preclinical investigations examining the behavioral effects of KOR antagonists have been in male rodents. Here, we...