Nano and Microparticulate Chitosan Based System for Formulation of Carvedilol Rapid Melt Tablet

• Main Authors: Ravindra Patil (Author), Vishal Pande (Author), Raju Sonawane (Author)
• פורמט: ספר
• יצא לאור: Tabriz University of Medical Sciences, 2015-06-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Purpose: In the present study rapid melt tablets (RMT's) of carvedilol were prepared by using ionotropic-gelated chitosan nanoparticles using a spray-drying method. Carvedilol is beta-adrenergic antagonist and its oral bioavailability is about 25-35% because of first pass metabolism. Methods: T...