Ultrastructural Changes Associated With the Enhanced Permeability of the Round Window Membrane Mediated by Ultrasound Microbubbles

• Main Authors: Yi-Chun Lin (Author), Hsin-Chien Chen (Author), Hang-Kang Chen (Author), Yuan-Yung Lin (Author), Chao-Yin Kuo (Author), Hao Wang (Author), Chia-Lien Hung (Author), Cheng-Ping Shih (Author), Chih-Hung Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The round window membrane (RWM) is the most common entryway for local drug and gene delivery into the inner ear, but its permeability can change the treatment outcome. We previously demonstrated a feasible and highly efficient approach using ultrasound-aided microbubble (USMB) cavitation to enhance...