Novel heterozygous mutation of CIITA gene presenting with recurrent infections and systemic lupus erythematosus

• Asıl Yazarlar: Aakash Chandran Chidambaram (Yazar), Jaikumar Govindaswamy Ramamoorthy (Yazar), Sriram Krishnamurthy (Yazar), Prabhu Manivannan (Yazar), Pediredla Karunakar (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wolters Kluwer Medknow Publications, 2021-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background: The expression of major histocompatibility complex (MHC) molecule is essential for homeostasis of the immune system. The expression of MHC-II is regulated by the master regulator for transcription, the Class II transactivator (CIITA) gene. Homozygous mutations affecting the CIITA gene re...