Repurposing drugs to treat trichinellosis: in vitro analysis of the anthelmintic activity of nifedipine and Chrysanthemum coronarium extract

• Main Authors: Mona Hasan El-Sayad (Author), Eman Sayed El-Wakil (Author), Zizi Hesham Moharam (Author), Naglaa Fathi Abd El-Latif (Author), Mosad A. Ghareeb (Author), Heba Elhadad (Author)
• Format: Book
• Published: BMC, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Albendazole is the most common benzimidazole derivative used for trichinellosis treatment but has many drawbacks. The quest for alternative compounds is, therefore, a target for researchers. This work aims to assess the in vitro anthelmintic effect of nifedipine, a calcium channel blocker,...