Erythrocyte Folyl Polyglutamate Synthetase Activity Profiling as a Potential Tool for the Prediction of Methotrexate Efficacy and Toxicity in Rheumatoid Arthritis

Methotrexate (MTX) is the cornerstone of therapy in the treatment of rheumatoid arthritis (RA). However, its efficacy and toxicity are variable and remain unpredictable. Interindividual variation in the metabolism of MTX by the enzyme folyl polyglutamate synthetase (FPGS) has been associated with re...

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Main Authors: Amar Kumar (Author), Mudassar Iqbal Arain (Author), Pooja Bhadbhade (Author), Ryan Funk (Author)
Format: Book
Published: MDPI AG, 2023-11-01T00:00:00Z.
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3rd Floor Main Library

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