Stealth lipid polymer hybrid nanoparticles loaded with rutin for effective brain delivery - comparative study with the gold standard (Tween 80): optimization, characterization and biodistribution

• Main Authors: Rania A. H. Ishak (Author), Nada M. Mostafa (Author), Amany O. Kamel (Author)
• 格式: 圖書
• 出版: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

The blood-brain barrier is considered the leading physiological obstacle hindering the transport of neurotherapeutics to brain cells. The application of nanotechnology coupled with surfactant coating is one of the efficacious tactics overcoming this barrier. The aim of this study was to develop lipi...